A single issue - either an indication, contraindication, interaction or an undesirable effect for a medicinal product, medication, device or procedure.

ClinicalUseDefinition
identifier
Business identifier for this issue
type
indication | contraindication | interaction | undesirable-effect | warning
category
A categorisation of the issue, primarily for dividing warnings into subject heading areas such as "Pregnancy", "Overdose"
subject
The medication, product, substance, device, procedure etc. for which this is an indication
status
Whether this is a current issue or one that has been retired etc
contraindication
Specifics for when this is a contraindication
diseaseSymptomProcedure
The situation that is being documented as contraindicating against this item
diseaseStatus
The status of the disease or symptom for the contraindication
comorbidity
A comorbidity (concurrent condition) or coinfection
indication
The indication which this is a contraidication for
applicability
An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements
otherTherapy
Information about use of the product in relation to other therapies described as part of the contraindication
relationshipType
The type of relationship between the product indication/contraindication and another therapy
treatment
Reference to a specific medication, substance etc. as part of an indication or contraindication
indication
Specifics for when this is an indication
diseaseSymptomProcedure
The situation that is being documented as an indicaton for this item
diseaseStatus
The status of the disease or symptom for the indication
comorbidity
A comorbidity or coinfection as part of the indication
intendedEffect
The intended effect, aim or strategy to be achieved
duration[x]
Timing or duration information
undesirableEffect
An unwanted side effect or negative outcome of the subject of this resource when being used for this indication
applicability
An expression that returns true or false, indicating whether the indication is applicable or not, after having applied its other elements
otherTherapy
The use of the medicinal product in relation to other therapies described as part of the indication
interaction
Specifics for when this is an interaction
interactant
The specific medication, product, food etc. or laboratory test that interacts
item[x]
The specific medication, product, food etc. or laboratory test that interacts
type
The type of the interaction e.g. drug-drug interaction, drug-lab test interaction
effect
The effect of the interaction, for example "reduced gastric absorption of primary medication"
incidence
The incidence of the interaction, e.g. theoretical, observed
management
Actions for managing the interaction
population
The population group to which this applies
library
Logic used by the clinical use definition
undesirableEffect
A possible negative outcome from the use of this treatment
symptomConditionEffect
The situation in which the undesirable effect may manifest
classification
High level classification of the effect
frequencyOfOccurrence
How often the effect is seen
warning
Critical environmental, health or physical risks or hazards. For example 'Do not operate heavy machinery', 'May cause drowsiness'
description
A textual definition of this warning, with formatting
code
A coded or unformatted textual definition of this warning